Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31178043 | 1.00 | CRBN (0.54) | CRBNDDB1BRD4 | |
| SCHEMBL23458425 | 0.88 | CRBN (0.44) | CRBNDDB1BRD4 | |
| Hydrochloric Acid SCHEMBL30938862 | 0.87 | CRBN (0.47) | CRBNDDB1BRD4 | |
| Hydrochloric Acid SCHEMBL30938865 | 0.86 | CRBN (0.48) | CRBNDDB1BRD4 | |
| SCHEMBL30938990 | 0.84 | CRBN (0.44) | CRBNDDB1BRD4 | |
| SCHEMBL30939003 | 0.83 | CRBN (0.45) | CRBNDDB1BRD4 | |
| SCHEMBL23453732 | 0.83 | CRBN (0.51) | CRBNDDB1BRD4 | |
| SCHEMBL29262107 | 0.82 | CRBN (0.48) | CRBNDDB1BRD4 | |
| SCHEMBL23453409 | 0.81 | CRBN (0.59) | CRBNDDB1BRD4 | |
| SCHEMBL23456486 | 0.81 | CRBN (0.50) | CRBNDDB1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121259-A1 | TARGETED PROTEIN DEGRADATION USING PRODRUGS OF BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2024-06-13 | — | — | WO | disclosed |
| WO-2024123195-A1 | TARGETED PROTEIN DEGRADATION USING PRODRUGS OF BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2024-06-13 | — | — | WO | disclosed |
| WO-2022255888-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |
| WO-2021105334-A1 | PIPERIDINE-2, 6-DIONE DERIVATIVES WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2021-06-03 | — | — | WO | disclosed |