Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.64 |
| ▸ | MET | P08581 | 18/20 | 0.56 |
| ▸ | AXL | P30530 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23458302 | 0.90 | CSF1R (0.64) | CSF1RMETAXL | |
| SCHEMBL23456850 | 0.90 | CSF1R (0.64) | CSF1RMETAXL | |
| SCHEMBL23456770 | 0.90 | CSF1R (0.64) | CSF1RMETAXL | |
| SCHEMBL23456812 | 0.89 | CSF1R (0.62) | CSF1RMETAXL | |
| SCHEMBL23456793 | 0.89 | CSF1R (0.64) | CSF1RMETAXL | |
| SCHEMBL23457019 | 0.88 | CSF1R (0.62) | CSF1RMETAXL | |
| SCHEMBL23456940 | 0.88 | CSF1R (0.62) | CSF1RMETAXL | |
| SCHEMBL23460728 | 0.88 | CSF1R (0.49) | CSF1RMETAXL | |
| SCHEMBL20022424 | 0.88 | CSF1R (0.61) | CSF1RMETAXL | |
| SCHEMBL23456799 | 0.87 | CSF1R (0.60) | CSF1RMETAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163448-A1 | QUINOLINE DERIVATIVES AS INHIBITORS OF AXL/MER RTK AND CSF1R | QURIENT CO., LTD. (KR) | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163448-A1 | QUINOLINE DERIVATIVES AS INHIBITORS OF AXL/MER RTK AND CSF1R | CSF1R, CSF3R, FLT3 | CSF1R 1/4885MET 16/4885AXL 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.