Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.51 |
| ▸ | MDM4 | O15151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24729097 | 1.00 | TLR2 (0.53) | TLR2MDM2MDM4TP53PTPN1 | |
| SCHEMBL30069166 | 1.00 | TLR2 (0.53) | TLR2MDM2MDM4TP53PTPN1 | |
| SCHEMBL29162900 | 1.00 | TLR2 (0.53) | TLR2MDM2MDM4TP53PTPN1 | |
| SCHEMBL22069859 | 0.97 | PTPN1 (0.49) | TLR2MDM2MDM4TP53PTPN1 | |
| SCHEMBL31133584 | 0.97 | PTPN1 (0.49) | TLR2MDM2MDM4TP53PTPN1 | |
| SCHEMBL30779239 | 0.97 | PTPN1 (0.49) | TLR2MDM2MDM4TP53PTPN1 | |
| SCHEMBL20732318 | 0.97 | PTPN1 (0.49) | TLR2MDM2MDM4TP53PTPN1 | |
| SCHEMBL20732316 | 0.97 | PTPN1 (0.49) | TLR2MDM2MDM4TP53PTPN1 | |
| SCHEMBL22069879 | 0.97 | PTPN1 (0.49) | TLR2MDM2MDM4TP53PTPN1 | |
| SCHEMBL5323666 | 0.93 | KMT2A (0.52) | TLR2MDM2MDM4TP53PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642190-A | Dimer-labeled precursor conjugated with a three-linker and radiotracer derived therefrom | 梅迪阿内泽有限公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2021103342-A1 | POLYETHYLENE GLYCOL CONJUGATED DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 重庆阿普格雷生物科技有限公司 | 2021-06-03 | — | — | WO | disclosed |