Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23469550 | 0.91 | KLKB1 (0.58) | KLKB1BTK | |
| SCHEMBL23469655 | 0.89 | KLKB1 (0.61) | KLKB1BTK | |
| SCHEMBL21746997 | 0.89 | KLKB1 (0.61) | KLKB1BTK | |
| SCHEMBL23469529 | 0.88 | KLKB1 (0.51) | KLKB1 | |
| SCHEMBL24105382 | 0.83 | KLKB1 (0.51) | KLKB1 | |
| SCHEMBL24918815 | 0.83 | KLKB1 (0.51) | KLKB1 | |
| SCHEMBL18815404 | 0.82 | BTK (0.59) | KLKB1BTK | |
| SCHEMBL20549564 | 0.82 | BTK (0.59) | KLKB1BTK | |
| SCHEMBL18815409 | 0.82 | BTK (0.59) | KLKB1BTK | |
| SCHEMBL22134224 | 0.80 | KLKB1 (0.71) | KLKB1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3612523-B1 | HETEROARYLCARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2021-06-09 | — | — | EP | disclosed |