Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 13/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13286051 | 0.96 | SLC9A3 (0.56) | SLC9A3 | |
| SCHEMBL19593602 | 0.89 | SLC9A3 (0.73) | SLC9A3 | |
| SCHEMBL13286045 | 0.86 | SLC9A3 (0.73) | SLC9A3 | |
| SCHEMBL13286048 | 0.86 | SLC9A3 (0.53) | SLC9A3 | |
| SCHEMBL2580547 | 0.85 | SLC9A3 (0.61) | SLC9A3 | |
| SCHEMBL2580551 | 0.85 | SLC9A3 (0.61) | SLC9A3 | |
| SCHEMBL2570705 | 0.84 | SLC9A3 (0.69) | SLC9A3 | |
| SCHEMBL13276313 | 0.84 | SLC9A3 (0.69) | SLC9A3 | |
| SCHEMBL2571112 | 0.83 | SLC9A3 (0.79) | SLC9A3 | |
| SCHEMBL2571107 | 0.83 | SLC9A3 (0.79) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939964-A1 | COMBINATIONS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS | Ardelyx, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |
| EP-3351248-B1 | COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS | ARDELYX INC (US) | 2021-06-09 | — | — | EP | disclosed |