Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.86 |
| ▸ | CD63 | P08962 | 4/20 | 0.86 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30029523 | 0.92 | SYK (1.00) | SYKCD63JAK2 | |
| SCHEMBL16820584 | 0.92 | SYK (1.00) | SYKCD63JAK2 | |
| SCHEMBL16820575 | 0.85 | SYK (1.00) | SYKCD63JAK2 | |
| SCHEMBL18996757 | 0.85 | SYK (0.86) | SYKCD63JAK2 | |
| SCHEMBL16820594 | 0.81 | SYK (1.00) | SYKCD63JAK2 | |
| SCHEMBL30029520 | 0.81 | SYK (1.00) | SYKCD63JAK2 | |
| SCHEMBL17536353 | 0.79 | SYK (0.80) | SYKCD63JAK2 | |
| SCHEMBL16848692 | 0.78 | SYK (0.63) | SYKCD63JAK2 | |
| SCHEMBL18996751 | 0.77 | SYK (0.83) | SYKCD63JAK2 | |
| SCHEMBL19865169 | 0.77 | SYK (0.73) | SYKCD63JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342773-B9 | SYK INHIBITORS | KRONOS BIO INC (US) | 2021-06-09 | — | — | EP | disclosed |