SCHEMBL2347199

SCHEMBL2347199

CC1=C(C=CC(=O)CO)C(C)(C)CCC1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 1/20 0.72
CYP1A2 P05177 2/20 0.69
ALDH1A1 P00352 10/20 0.55
PTGS1 P23219 4/20 0.55
LMNA P02545 2/20 0.55
DRD3 P35462 2/20 0.55
SLCO1B3 Q9NPD5 2/20 0.55
SLCO1B1 Q9Y6L6 2/20 0.55
MAPT P10636 7/20 0.54
RARA P10276 6/20 0.54
RARB P10826 6/20 0.54
RARG P13631 6/20 0.54
CYP3A4 P08684 6/20 0.54
RXRA P19793 5/20 0.54
MAPK1 P28482 3/20 0.54
APP P05067 3/20 0.54
SNCA P37840 3/20 0.54
ALOX15 P16050 3/20 0.54
RXRB P28702 2/20 0.54
RXRG P48443 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28602034 1.00 HAO1 (0.72) HAO1CYP1A2ALDH1A1PTGS1LMNA
SCHEMBL1761126 0.90 HAO1 (0.86) HAO1CYP1A2ALDH1A1PTGS1LMNA
SCHEMBL29012640 0.89 HAO1 (0.74) HAO1CYP1A2ALDH1A1PTGS1LMNA
SCHEMBL1404271 0.88 HAO1 (0.72) HAO1CYP1A2ALDH1A1PTGS1LMNA
SCHEMBL1404273 0.88 HAO1 (0.72) HAO1CYP1A2ALDH1A1PTGS1LMNA
SCHEMBL2130233 0.88 HAO1 (0.72) HAO1CYP1A2ALDH1A1PTGS1LMNA
SCHEMBL1275491 0.85 HAO1 (0.68) HAO1CYP1A2ALDH1A1PTGS1LMNA
SCHEMBL1275512 0.85 HAO1 (0.68) HAO1CYP1A2ALDH1A1PTGS1LMNA
SCHEMBL2345012 0.85 HAO1 (0.77) HAO1CYP1A2ALDH1A1PTGS1LMNA
SCHEMBL2345010 0.85 HAO1 (0.77) HAO1CYP1A2ALDH1A1PTGS1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935570-B1 CAROTENE HYDROXYLASE AND ITS USE FOR PRODUCING CAROTENOIDS DSM IP ASSETS BV (NL) 2018-09-19 EP claimed
US-10301259-B2 Beta-cryptoxanthin from plant source and a process for its preparation OMNIACTIVE HEALTH TECHNOLOGIES LIMITED (IN) 2019-05-28 US disclosed
US-20170334845-A1 BETA-CRYPTOXANTHIN FROM PLANT SOURCE AND A PROCESS FOR ITS PREPARATION OMNIACTIVE HEALTH TECHNOLOGIES LIMITED (IN) 2017-11-23 US disclosed
US-9771323-B2 Beta-cryptoxanthin from plant source and a process for its preparation OMNIACTIVE HEALTH TECHNOLOGIES LIMITED (IN) 2017-09-26 US disclosed
US-20150361040-A1 BETA-CRYPTOXANTHIN FROM PLANT SOURCE AND A PROCESS FOR ITS PREPARATION OMNIACTIVE HEALTH TECHNOLOGIES LIMITED (IN) 2015-12-17 US disclosed
EP-2948428-A2 BETA-CRYPTOXANTHIN FROM PLANT SOURCE AND A PROCESS FOR ITS PREPARATION Omniactive Health Technologies Ltd. (IN) 2015-12-02 EP disclosed
WO-2014115037-A2 BETA-CRYPTOXANTHIN FROM PLANT SOURCE AND A PROCESS FOR ITS PREPARATION OMNIACTIVE HEALTH TECHNOLOGIES LTD. (IN) 2014-07-31 WO disclosed
US-20120156718-A1 Production of Ketocarotenoids in Plants BASF PLANT SCIENCE GMBH (DE) 2012-06-21 US disclosed
EP-2361245-A1 HYBRID -IONONE AND CURCUMIN MOLECULES AS ANTICANCER AGENTS TRT Pharma Inc . (CA) 2011-08-31 EP disclosed
EP-2199399-A1 Production of ketocarotenoids in plants BASF Plant Science GmbH (DE) 2010-06-23 EP disclosed
JP-2000143688-A PRODUCTION OF ZEAXANTHIN MONO-BETA-GLUCOSIDE KURARAY CO LTD 2000-05-26 JP disclosed
US-4594456-A Racemic and optically active 3-hydroxy-alpha-cyclocitral, its acetals and optically active 3-oxo-alpha-cyclocitral acetals, and their preparation BASF AKTIENGESELLSCHAFT (DE) 1986-06-10 US disclosed
US-4296259-A Preparation of a 1,4-pentadien-3-ol HOFFMANN-LA ROCHE INC. (US) 1981-10-20 US disclosed
US-4296259-A Preparation of a 1,4-pentadien-3-ol HOFFMANN-LA ROCHE INC. (US) 1981-10-20 US disclosed
US-4193850-A ELECTROLYSIS HOFFMANN-LA ROCHE INC. (US) 1980-03-18 US disclosed
US-4156100-A INTERMEDIATES FOR OPTICALLY ACTIVE CAROTENOIDS HOFFMANN-LA ROCHE INC. (US) 1979-05-22 US disclosed
US-4095038-A INTERMEDIATES IN THE PRODUCTION OF CAROTENOIDS HOFFMANN-LA ROCHE INC. (US) 1978-06-13 US disclosed
US-4072715-A CAROTENOIDS HOFFMANN-LA ROCHE INC. (US) 1978-02-07 US disclosed
US-4026949-A INTERMEDIATES FOR CAROTENOIDS HOFFMANN-LA ROCHE INC. (US) 1977-05-31 US disclosed
US-3988205-A BY FERMENTATIVELY HYDROGENATING AND REDUCING KETOISOPHORONE HOFFMANN-LA ROCHE INC. (US) 1976-10-26 US disclosed