Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472283 | 0.86 | TLR7 (0.45) | TLR7TLR8CYP1A2CYP2D6 | |
| SCHEMBL23472561 | 0.86 | TLR8 (0.48) | TLR7TLR8CYP1A2CYP2D6 | |
| SCHEMBL23472598 | 0.84 | TLR8 (0.43) | TLR7TLR8CCNKCDK12 | |
| SCHEMBL13195051 | 0.84 | TLR7 (0.68) | TLR7TLR8CYP1A2CYP2D6 | |
| SCHEMBL20219355 | 0.83 | TLR7 (0.64) | TLR7TLR8CYP1A2CYP2D6 | |
| SCHEMBL20219323 | 0.83 | TLR8 (0.49) | TLR7TLR8 | |
| SCHEMBL15470008 | 0.83 | TLR8 (0.49) | TLR7TLR8 | |
| SCHEMBL13194976 | 0.81 | TLR8 (0.64) | TLR7TLR8CYP1A2CYP2D6 | |
| SCHEMBL15469989 | 0.80 | TLR8 (0.48) | TLR7TLR8 | |
| SCHEMBL13194968 | 0.80 | TLR8 (0.62) | TLR7TLR8CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |