Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.35 |
| ▸ | MERTK | Q12866 | 2/20 | 0.35 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20219561 | 0.88 | CYP2D6 (0.46) | CYP2D6CYP2C9CYP1A2CYP3A4TLR7 | |
| SCHEMBL13195672 | 0.87 | CYP2D6 (0.55) | CYP2D6CYP2C9CYP1A2CYP3A4TLR7 | |
| SCHEMBL23472498 | 0.80 | CYP1A2 (0.56) | CYP2D6CYP2C9CYP1A2CYP3A4TLR7 | |
| SCHEMBL15469709 | 0.79 | CYP2D6 (0.42) | CYP2D6CYP2C9CYP1A2CYP3A4TLR7 | |
| SCHEMBL13195772 | 0.75 | CYP1A2 (0.53) | CYP2D6CYP2C9CYP1A2CYP3A4TLR7 | |
| SCHEMBL23472616 | 0.74 | CYP1A2 (0.50) | CYP2D6CYP2C9CYP1A2CYP3A4TLR7 | |
| SCHEMBL13195678 | 0.74 | TLR7 (0.60) | CYP2D6CYP1A2CYP3A4TLR7 | |
| SCHEMBL23472639 | 0.74 | CYP1A2 (0.50) | CYP2D6CYP2C9CYP1A2CYP3A4TLR7 | |
| SCHEMBL13195688 | 0.73 | CYP1A2 (0.51) | CYP2D6CYP2C9CYP1A2CYP3A4TLR7 | |
| SCHEMBL13195033 | 0.72 | TLR8 (0.67) | CYP2D6CYP1A2CYP3A4TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |