SCHEMBL234737

SCHEMBL234737

CC(C)COC(=O)CC(C)(C)CC(=O)OCC(C)C

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.33
PPARG P37231 1/20 0.33
NCOA2 Q15596 1/20 0.33
NCOA1 Q15788 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13863995 0.92 TDP1 (0.41) TSHRALDH1A1TDP1L3MBTL1KDM4E
SCHEMBL6892165 0.90 TSHR (0.39) TSHRALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL6892214 0.86 TSHR (0.43) TSHRALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL6894038 0.86 TSHR (0.37) TSHRALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL31058602 0.84 TSHR (0.42) TSHRALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL6892173 0.83 MAPT (0.41) TSHRALDH1A1TDP1MAPTKDM4E
SCHEMBL7155936 0.83 TSHR (0.41) TSHRALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL5972501 0.83 TSHR (0.41) TSHRALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL2456917 0.82 TSHR (0.37) TSHRALDH1A1TDP1L3MBTL1PPARG
SCHEMBL5972522 0.81 TSHR (0.39) TSHRALDH1A1TDP1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186660-B2 Internal electron donor compound for preparing α-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO., LTD. 2021-11-30 US claimed
US-20190218317-A1 INTERNAL ELECTRON DONOR COMPOUND FOR PREPARING ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT YINGKOU XIANGYANG CATALYST CO LTD (CN) 2019-07-18 US claimed
US-10287371-B2 Internal electron donor compound for preparing α-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO., LTD. (CN) 2019-05-14 US claimed
US-20160229935-A1 Internal Electron Donor Compound for Preparing Alpha-olefin Polymerization Catalyst Component DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2016-08-11 US claimed
EP-1685090-A1 ANDROGEN RECEPTOR MODULATORS KARO BIO AB (SE) 2006-08-02 EP claimed
WO-2005042464-A1 ANDROGEN RECEPTOR MODULATORS KARO BIO AB (SE) 2005-05-12 WO claimed
CN-116194520-B Butene-1 polymer compositions with short crystallization times 巴塞尔聚烯烃意大利有限公司 2025-05-13 CN disclosed
CN-116194520-A Butene-1 polymer compositions with short crystallization times 巴塞尔聚烯烃意大利有限公司 2023-05-30 CN disclosed
US-20220081497-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-03-17 US disclosed
US-11186660-B2 Internal electron donor compound for preparing α-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO., LTD. 2021-11-30 US disclosed
EP-3908614-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2021-11-17 EP disclosed
CN-113179643-A Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2021-07-27 CN disclosed
EP-2945971-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2020-12-02 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed
EP-1082359-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SRL (IT) 2006-07-19 EP disclosed
US-6541582-B1 Catalytic polymerization of propylene via magnesium chloride, titanium chloride, and beta-substituted glutarates; stereospecificity; high isotactic index expressed in terms of high xylene insolubility BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-04-01 US disclosed
EP-1082359-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2001-03-14 EP disclosed
WO-2000055215-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2000-09-21 WO disclosed