⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431111 | 1.00 | — | — | |
| SCHEMBL76203 | 1.00 | — | — | |
| SCHEMBL1873213 | 1.00 | — | — | |
| SCHEMBL28564399 | 1.00 | — | — | |
| SCHEMBL11053806 | 1.00 | — | — | |
| SCHEMBL23499212 | 0.82 | — | — | |
| SCHEMBL1875275 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8937831 | 0.82 | — | — | |
| Water SCHEMBL20397372 | 0.82 | — | — | |
| Water SCHEMBL21065438 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008274-B2 | P1-(2′-deoxycytidine 5′-)P4-(uridine 5′-)tetraphosphate, tetra-(alkali metal) salt, for treating sinusitis | INSPIRE PHARMACEUTICALS, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20090306010-A1 | P1-(2'-DEOXYCYTIDINE 5'-)P4-(URIDINE 5'-)TETRAPHOSPHATE, TETRA-(ALKALI METAL) SALT, FOR TREATING DISORDERS | MERCK SHARP & DOHME CORP. | 2009-12-10 | — | — | US | disclosed |
| US-7531525-B2 | P1-(2′-deoxycytidine 5′-)P4-(uridine 5′-)tetraphosphate, tetra-(alkali metal) salt, for treating cystic fibrosis | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-05-12 | — | — | US | disclosed |
| US-20070197454-A1 | P1-(2'-DEOXYCYTIDINE 5'-)P4-(URIDINE 5'-)TETRAPHOSPHATE, TETRA-(ALKALI METAL) SALT, FOR TREATING DISORDERS | MERCK SHARP & DOHME LLC | 2007-08-23 | — | — | US | disclosed |
| US-7223744-B2 | Pharmaceutical formulation comprising dinucleoside polyphosphates and salts thereof | INSPIRE PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-20050085439-A1 | Pharmaceutical formulation comprising dinucleoside polyphosphates and salts thereof | MERCK SHARP & DOHME LLC | 2005-04-21 | — | — | US | disclosed |