Isatoribine

Isatoribine

SCHEMBL23475855

Nc1nc2c(sc(=O)n2C2OC(CO)C(O)C2O)c(=O)[nH]1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PNP P00491 1/20 0.67
TLR7 Q9NYK1 13/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
CYP3A4 P08684 1/20 0.53
MAPT P10636 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isatoribine SCHEMBL12808801 1.00 PNP (0.67) PNPTLR7MEN1KMT2ACYP3A4
Isatoribine SCHEMBL1758185 1.00 PNP (0.67) PNPTLR7MEN1KMT2ACYP3A4
Isatoribine SCHEMBL6975944 1.00 PNP (0.67) PNPTLR7MEN1KMT2ACYP3A4
Isatoribine SCHEMBL8664086 1.00 PNP (0.67) PNPTLR7MEN1KMT2ACYP3A4
Isatoribine SCHEMBL10148062 1.00 PNP (0.67) PNPTLR7MEN1KMT2ACYP3A4
Isatoribine SCHEMBL12112066 1.00 PNP (0.67) PNPTLR7MEN1KMT2ACYP3A4
Isatoribine SCHEMBL10117797 1.00 PNP (0.67) PNPTLR7MEN1KMT2ACYP3A4
Isatoribine SCHEMBL6905340 1.00 PNP (0.67) PNPTLR7MEN1KMT2ACYP3A4
Isatoribine SCHEMBL1276851 0.99 PNP (0.65) PNPTLR7MEN1KMT2ACYP3A4
SCHEMBL6976713 0.91 TLR7 (0.57) PNPTLR7MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250222100-A1 COMPLETE TOLEROGENIC ADJUVANT AND METHODS OF USING THE SAME THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-07-10 US disclosed
WO-2021110120-A1 ANTI-TUMOR VACCINE MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF 华中师范大学 2021-06-10 WO disclosed