Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.57 |
| ▸ | EPOR | P19235 | 1/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23475940 | 1.00 | GLP1R (0.57) | GLP1REPORNMT2NMT1FOLH1 | |
| SCHEMBL18186925 | 1.00 | GLP1R (0.57) | GLP1REPORNMT2NMT1FOLH1 | |
| SCHEMBL23475890 | 1.00 | GLP1R (0.57) | GLP1REPORNMT2NMT1FOLH1 | |
| SCHEMBL23475961 | 1.00 | GLP1R (0.57) | GLP1REPORNMT2NMT1FOLH1 | |
| SCHEMBL16830716 | 1.00 | GLP1R (0.57) | GLP1REPORNMT2NMT1FOLH1 | |
| SCHEMBL26257038 | 0.94 | GLP1R (0.54) | GLP1REPORNMT2NMT1FOLH1 | |
| SCHEMBL26256080 | 0.94 | GLP1R (0.59) | GLP1REPORNMT2NMT1SIRT2 | |
| SCHEMBL26257050 | 0.94 | GLP1R (0.59) | GLP1REPORNMT2NMT1SIRT2 | |
| SCHEMBL16853379 | 0.94 | GLP1R (0.54) | GLP1REPORNMT2NMT1FOLH1 | |
| SCHEMBL24712871 | 0.92 | GLP1R (0.65) | GLP1REPORFOLH1GLO1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257979-A1 | LONG-ACTING DUAL GIP/GLP-1 PEPTIDE CONJUGATES AND METHODS OF USE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-12-15 | — | — | WO | disclosed |
| WO-2021113535-A1 | PEPTIDE CONJUGATES AND METHODS OF USE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-06-10 | — | — | WO | disclosed |
| WO-2021113524-A2 | GLP2 RECEPTOR AGONISTS AND METHODS OF USE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-06-10 | — | — | WO | disclosed |