Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 12/20 | 0.37 |
| ▸ | SLC6A4 known ✓ | P31645 | 11/20 | 0.37 |
| ▸ | SLC6A3 known ✓ | Q01959 | 8/20 | 0.37 |
| ▸ | ADRB2 known ✓ | P07550 | 2/20 | 0.37 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.37 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.31 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3305446 | 0.98 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3ADRB2MLNR | |
| Bromide SCHEMBL11125370 | 0.90 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3ADRB2MLNR | |
| Bromide SCHEMBL11125786 | 0.90 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3ADRB2MLNR | |
| Pyrrole SCHEMBL23500114 | 0.89 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3ADRB2MLNR | |
| SCHEMBL5712863 | 0.88 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3ADRB2MLNR | |
| SCHEMBL6712356 | 0.88 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3ADRB2MLNR | |
| SCHEMBL6833197 | 0.88 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3ADRB2MLNR | |
| SCHEMBL9858373 | 0.88 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3ADRB2MLNR | |
| Hydrochloric Acid SCHEMBL8366765 | 0.87 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3ADRB2MLNR | |
| Hydrochloric Acid SCHEMBL21817059 | 0.87 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3ADRB2MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698631-B1 | IONIC LIQUID, METHOD FOR PRODUCING SAME, DOUBLE LAYER CAPACITOR COMPRISING SAME, AND LITHIUM BATTERY | NAT INST OF ADVANCED IND SCIEN (JP) | 2011-08-10 | — | — | EP | disclosed |
| US-20070099079-A1 | Ionic liquid, method for producing same, double layer capacitor comprising same, and lithium battery | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1698631-A1 | IONIC LIQUID, METHOD FOR PRODUCING SAME, DOUBLE LAYER CAPACITOR COMPRISING SAME, AND LITHIUM BATTERY | National Institute of Advanced Industrial Science and Technology (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099079-A1 | Ionic liquid, method for producing same, double layer capacitor comprising same, and lithium battery | CLCN2, CACNA1F, CACNB3 | SLC6A2 1120/4885SLC6A4 1984/4885SLC6A3 888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.