Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22274929 | 0.88 | GAA (0.33) | PDCD1CD274SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23480261 | 0.84 | — | — | |
| SCHEMBL9851667 | 0.83 | DRD4 (0.33) | — | |
| SCHEMBL19262311 | 0.82 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3USP2 | |
| SCHEMBL13713119 | 0.81 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3USP2 | |
| SCHEMBL23995516 | 0.76 | KDM4E (0.31) | — | |
| SCHEMBL18520587 | 0.74 | MEN1 (0.34) | PDCD1CD274MEN1POLBKMT2A | |
| SCHEMBL19046831 | 0.74 | — | — | |
| SCHEMBL19783894 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL2583995 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113679-A1 | DIMERIC COMPOUNDS AS STING AGONISTS | MERSANA THERAPEUTICS, INC. (US) | 2021-06-10 | — | — | WO | disclosed |