Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158642 | 0.73 | POLB (0.51) | MAPK1KCNH2 | |
| SCHEMBL13156892 | 0.72 | — | — | |
| SCHEMBL8000759 | 0.69 | POLB (0.56) | LMNAMAPK1KCNH2 | |
| SCHEMBL11987826 | 0.68 | POLB (0.59) | LMNAMAPK1KCNH2 | |
| SCHEMBL11987816 | 0.68 | POLB (0.59) | LMNAMAPK1KCNH2 | |
| SCHEMBL18424414 | 0.66 | POLB (0.33) | LMNAMAPK1KCNH2 | |
| SCHEMBL24153581 | 0.62 | POLB (0.34) | LMNAMAPK1KCNH2 | |
| SCHEMBL11987809 | 0.62 | KCNH2 (0.41) | LMNAMAPK1KCNH2 | |
| SCHEMBL11987805 | 0.62 | KCNH2 (0.30) | LMNAMAPK1KCNH2 | |
| SCHEMBL19674410 | 0.62 | POLB (0.31) | LMNAMAPK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113809-A1 | ARYLAMIDES AND METHODS OF USE THEREOF | GENZYME CORPORATION (US) | 2021-06-10 | — | — | WO | disclosed |