SCHEMBL23483076

SCHEMBL23483076

C[C@H](CCC(=O)O)C1CCC2C3C(CC[C@@]21C)[C@@]1(C)CCCC[C@H]1C[C@@H]3O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 11/20 1.00
NR1H4 Q96RI1 6/20 1.00
MEN1 O00255 3/20 0.79
KMT2A Q03164 3/20 0.79
ABCB11 O95342 2/20 0.79
SLC10A2 Q12908 2/20 0.79
LMNA P02545 2/20 0.79
TDP1 Q9NUW8 2/20 0.79
CYP2C19 P33261 1/20 0.79
CHRM2 P08172 1/20 0.79
ADRA2A P08913 1/20 0.79
ADRA1A P35348 1/20 0.79
ENPP2 Q13822 1/20 0.79
SLC10A1 Q14973 1/20 0.79
CISD1 Q9NZ45 1/20 0.79
CYP3A4 P08684 1/20 0.79
AKR1B10 O60218 1/20 0.72
AKR1B1 P15121 1/20 0.72
EFNA1 P20827 1/20 0.72
EPHA2 P29317 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17641251 1.00 GPBAR1 (1.00) GPBAR1NR1H4MEN1KMT2AABCB11
SCHEMBL22626977 1.00 GPBAR1 (1.00) GPBAR1NR1H4MEN1KMT2AABCB11
SCHEMBL19200988 1.00 GPBAR1 (1.00) GPBAR1NR1H4MEN1KMT2AABCB11
SCHEMBL22627010 1.00 GPBAR1 (1.00) GPBAR1NR1H4MEN1KMT2AABCB11
SCHEMBL24404377 1.00 GPBAR1 (1.00) GPBAR1NR1H4MEN1KMT2AABCB11
SCHEMBL24437428 1.00 GPBAR1 (1.00) GPBAR1NR1H4MEN1KMT2AABCB11
SCHEMBL23483146 1.00 GPBAR1 (1.00) GPBAR1NR1H4MEN1KMT2AABCB11
SCHEMBL24897216 1.00 GPBAR1 (1.00) GPBAR1NR1H4MEN1KMT2AABCB11
SCHEMBL21710850 1.00 GPBAR1 (1.00) GPBAR1NR1H4MEN1KMT2AABCB11
SCHEMBL17641190 1.00 GPBAR1 (1.00) GPBAR1NR1H4MEN1KMT2AABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021109791-A1 METHOD FOR SYNTHESIZING URSODEOXYCHOLIC ACID USING BA AS RAW MATERIAL 江苏佳尔科药业集团股份有限公司 2021-06-10 WO disclosed