Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23459488 | 0.73 | PIK3CD (0.36) | PIK3CDPIK3CBPIK3CGKDM4EMEN1 | |
| SCHEMBL23485526 | 0.67 | ROCK1 (0.45) | PIK3CDPIK3CBPIK3CG | |
| SCHEMBL30274193 | 0.66 | CDK2 (0.58) | PIK3CDPIK3CBPIK3CGKDM4EMEN1 | |
| SCHEMBL23459458 | 0.65 | ROCK1 (0.33) | PIK3CDPIK3CBPIK3CG | |
| SCHEMBL23485534 | 0.65 | CDC7 (0.38) | PIK3CDPIK3CBPIK3CG | |
| SCHEMBL23485677 | 0.65 | CDK4 (0.39) | PIK3CDPIK3CBPIK3CG | |
| SCHEMBL30274290 | 0.65 | CDC7 (0.47) | PIK3CDPIK3CBPIK3CG | |
| SCHEMBL23460266 | 0.64 | PIK3CD (0.36) | PIK3CDPIK3CBPIK3CG | |
| SCHEMBL23485535 | 0.63 | PRKCQ (0.44) | PIK3CDPIK3CBPIK3CG | |
| SCHEMBL30274213 | 0.63 | PRKCQ (0.44) | PIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113492-A1 | CYCLIC COMPOUNDS AND METHODS OF USING SAME | SCHRÖDINGER, INC. (US) | 2021-06-10 | — | — | WO | disclosed |