Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 9/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 7/20 | 0.52 |
| ▸ | ITGAV | P06756 | 2/20 | 0.45 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 3/20 | 0.42 |
| ▸ | PRCP | P42785 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23489171 | 0.85 | ITGB1 (0.57) | ITGB1ITGA5ITGAVITGB8ITGAL | |
| Hydrochloric Acid SCHEMBL23455540 | 0.84 | ITGB1 (0.56) | ITGB1ITGA5ITGAVITGB8ITGAL | |
| Hydrochloric Acid SCHEMBL28884207 | 0.84 | ITGB1 (0.56) | ITGB1ITGA5ITGAVITGB8ITGAL | |
| SCHEMBL23978757 | 0.83 | ITGB1 (0.51) | ITGB1ITGA5ITGAVITGB8ITGAL | |
| SCHEMBL23455597 | 0.83 | ITGB1 (0.53) | ITGB1ITGA5ITGAVITGB8ITGAL | |
| SCHEMBL23518384 | 0.83 | ITGB1 (0.53) | ITGB1ITGA5ITGAVITGB8ITGAL | |
| SCHEMBL23489448 | 0.82 | ITGB1 (0.55) | ITGB1ITGA5ITGAVITGB8ITGAL | |
| SCHEMBL23455570 | 0.81 | ITGB1 (0.66) | ITGB1ITGA5ITGAVITGB8ITGAL | |
| SCHEMBL28884224 | 0.81 | ITGB1 (0.57) | ITGB1ITGA5ITGAVITGB8ITGAL | |
| SCHEMBL23489408 | 0.79 | ITGB1 (0.48) | ITGB1ITGA5ITGAVITGB8ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530180-B2 | Alpha-5 beta-1 inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-20 | — | — | US | disclosed |
| US-20210171455-A1 | ALPHA-5 BETA-1 INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171455-A1 | ALPHA-5 BETA-1 INHIBITORS | SCN5A, PSMA5, API5 | ITGB1 138/4885ITGA5 19/4885ITGAV 1756/4885 |
| US-11530180-B2 | Alpha-5 beta-1 inhibitors | SCN5A, PSMA5, API5 | ITGB1 138/4885ITGA5 19/4885ITGAV 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.