⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140999 | 0.78 | — | — | |
| SCHEMBL17831795 | 0.78 | — | — | |
| SCHEMBL25894193 | 0.78 | — | — | |
| SCHEMBL62171 | 0.78 | — | — | |
| SCHEMBL3620693 | 0.78 | — | — | |
| SCHEMBL10140982 | 0.78 | — | — | |
| SCHEMBL1354775 | 0.73 | — | — | |
| SCHEMBL77862 | 0.73 | — | — | |
| SCHEMBL24309072 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL11286597 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022012623-A1 | DEGRADATION OF (EGFR) BY CONJUGATION OF EGFR INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2022-01-20 | — | — | WO | disclosed |
| WO-2021113625-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2021-06-10 | — | — | WO | disclosed |