Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.73 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.73 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.73 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.73 |
| ▸ | BLM | P54132 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | HTR2C | P28335 | 3/20 | 0.70 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.70 |
| ▸ | HRH1 | P35367 | 2/20 | 0.70 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22394825 | 1.00 | CYP2D6 (0.76) | CYP2D6TSHRCYP1A2LMNACYP2C9 | |
| SCHEMBL27203717 | 1.00 | CYP2D6 (0.76) | CYP2D6TSHRCYP1A2LMNACYP2C9 | |
| SCHEMBL22394823 | 1.00 | CYP2D6 (0.76) | CYP2D6TSHRCYP1A2LMNACYP2C9 | |
| SCHEMBL30869410 | 1.00 | CYP2D6 (0.76) | CYP2D6TSHRCYP1A2LMNACYP2C9 | |
| SCHEMBL23494999 | 1.00 | CYP2D6 (0.76) | CYP2D6TSHRCYP1A2LMNACYP2C9 | |
| SCHEMBL22394824 | 1.00 | CYP2D6 (0.76) | CYP2D6TSHRCYP1A2LMNACYP2C9 | |
| SCHEMBL19136281 | 1.00 | CYP2D6 (0.76) | CYP2D6TSHRCYP1A2LMNACYP2C9 | |
| SCHEMBL23495020 | 0.89 | CYP2D6 (0.61) | CYP2D6TSHRCYP1A2LMNACYP2C9 | |
| SCHEMBL23495018 | 0.89 | CYP2D6 (0.61) | CYP2D6TSHRCYP1A2LMNACYP2C9 | |
| SCHEMBL23495019 | 0.89 | CYP2D6 (0.61) | CYP2D6TSHRCYP1A2LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704117-B1 | AZABICYCLO DERIVATIVES FOR TREATING OCULAR DISORDERS | ALCON INC (CH) | 2026-01-28 | — | — | EP | disclosed |
| US-12247028-B2 | Azabicyclo and diazepine derivatives | ALCON INC. (CH) | 2025-03-11 | — | — | US | disclosed |
| US-20240132497-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | ALCON INC. (CH) | 2024-04-25 | — | — | US | disclosed |
| US-11884666-B2 | Azabicyclo and diazepine derivatives | ALCON INC. (CH) | 2024-01-30 | — | — | US | disclosed |
| US-20220267328-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | ALCON INC. (CH) | 2022-08-25 | — | — | US | disclosed |
| US-11306090-B2 | Azabicyclo and diazepine derivatives | ALCON INC. (CH) | 2022-04-19 | — | — | US | disclosed |
| US-20210179616-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | ALCON INC. (CH) | 2021-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11884666-B2 | Azabicyclo and diazepine derivatives | CHRM3, CHRM5, CHRNA5 | CYP2D6 1374/4885TSHR 202/4885CYP1A2 906/4885 |
| US-20240132497-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | CHRM3, CHRM5, CHRNA5 | CYP2D6 1374/4885TSHR 202/4885CYP1A2 906/4885 |
| US-20210179616-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | CHRM3, CHRM5, CHRNA5 | CYP2D6 1374/4885TSHR 202/4885CYP1A2 906/4885 |
| US-20220267328-A1 | AZABICYCLO AND DIAZEPINE DERIVATIVES | CHRM3, CHRM5, CHRNA5 | CYP2D6 1374/4885TSHR 202/4885CYP1A2 906/4885 |
| US-12247028-B2 | Azabicyclo and diazepine derivatives | CHRM3, CHRM5, CHRNA5 | CYP2D6 1374/4885TSHR 202/4885CYP1A2 906/4885 |
| US-11306090-B2 | Azabicyclo and diazepine derivatives | CHRM3, CHRM5, CHRNA5 | CYP2D6 1374/4885TSHR 202/4885CYP1A2 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.