Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.32 |
| ▸ | CDK2 | P24941 | 3/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23508128 | 0.89 | MEN1 (0.34) | HSD17B10GSK3BCDK2 | |
| SCHEMBL23508347 | 0.89 | GSK3B (0.34) | HSD17B10GSK3BCDK2 | |
| SCHEMBL23497842 | 0.88 | KLK1 (0.36) | HSD17B10GSK3BCNR1 | |
| SCHEMBL30012124 | 0.88 | KLK1 (0.36) | HSD17B10GSK3BCNR1 | |
| SCHEMBL23497830 | 0.87 | HSD17B10 (0.46) | HSD17B10 | |
| SCHEMBL23497559 | 0.86 | GRIN1 (0.33) | HSD17B10GSK3BCDK2NTRK1NTRK2 | |
| SCHEMBL23508254 | 0.84 | CDK12 (0.40) | CDK2 | |
| SCHEMBL23508105 | 0.83 | CDK2 (0.36) | HSD17B10GSK3BCDK2 | |
| SCHEMBL23508057 | 0.83 | GSK3B (0.36) | GSK3BCDK2 | |
| Hydrochloric Acid SCHEMBL23497853 | 0.83 | GSK3B (0.35) | GSK3BCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073072-A1 | PYRAZOLOTRIAZINES | Bayer Aktiengesellschaft (DE) | 2022-10-19 | — | — | EP | disclosed |
| WO-2021116178-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-17 | — | — | WO | disclosed |