Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMTK3 | Q96Q04 | 2/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.78 |
| ▸ | NTRK1 | P04629 | 8/20 | 0.67 |
| ▸ | PRKCQ | Q04759 | 7/20 | 0.67 |
| ▸ | KDR | P35968 | 7/20 | 0.67 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.67 |
| ▸ | PRKCA | P17252 | 5/20 | 0.67 |
| ▸ | PRKCH | P24723 | 5/20 | 0.67 |
| ▸ | PRKCI | P41743 | 5/20 | 0.67 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.67 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.67 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.67 |
| ▸ | MAP3K11 | Q16584 | 5/20 | 0.67 |
| ▸ | PRKCG | P05129 | 4/20 | 0.67 |
| ▸ | PRKCB | P05771 | 4/20 | 0.67 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.67 |
| ▸ | MYLK | Q15746 | 4/20 | 0.67 |
| ▸ | MAP3K9 | P80192 | 4/20 | 0.67 |
| ▸ | MAP3K10 | Q02779 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13169944 | 0.88 | LMTK3 (1.00) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL5951557 | 0.88 | LMTK3 (1.00) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL29394491 | 0.88 | LMTK3 (1.00) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL24393927 | 0.88 | LMTK3 (1.00) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL16112156 | 0.88 | LMTK3 (1.00) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL31119069 | 0.88 | LMTK3 (1.00) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL20865173 | 0.85 | LMTK3 (0.85) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL20865167 | 0.83 | LMTK3 (0.81) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| SCHEMBL20865155 | 0.82 | LMTK3 (0.79) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ | |
| K-252A SCHEMBL24112155 | 0.81 | NTRK1 (1.00) | LMTK3SMN1; SMN2PDK1NTRK1PRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119183-A1 | TRICYCLIC COMPOUNDS WITH OMA1/OPA1 MODULATORY PROPERTIES | 712 NORTH, INC. (US) | 2021-06-17 | — | — | WO | claimed |
| US-20230065809-A1 | TRICYCLIC COMPOUNDS WITH OMA1/OPA1 MODULATORY PROPERTIES | 712 NORTH INC. | 2023-03-02 | — | — | US | disclosed |
| WO-2021119183-A1 | TRICYCLIC COMPOUNDS WITH OMA1/OPA1 MODULATORY PROPERTIES | 712 NORTH, INC. (US) | 2021-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230065809-A1 | TRICYCLIC COMPOUNDS WITH OMA1/OPA1 MODULATORY PROPERTIES | OPA1, OLA1, ACOX1 | LMTK3 3006/4885SMN1; SMN2 2071/4885PDK1 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.