Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | HTR2C | P28335 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501891 | 1.00 | NPSR1 (0.60) | NPSR1NFKB1BLMHTR1AHTR2A | |
| SCHEMBL23501894 | 0.93 | TRPV1 (0.64) | NPSR1NFKB1BLMHTR1AHTR2A | |
| SCHEMBL23501893 | 0.93 | TRPV1 (0.64) | NPSR1NFKB1BLMHTR1AHTR2A | |
| SCHEMBL27964771 | 0.91 | NPSR1 (0.60) | NPSR1NFKB1BLMHTR1AHTR2A | |
| SCHEMBL11486816 | 0.89 | NPSR1 (0.59) | NPSR1NFKB1BLMHTR1AHTR2A | |
| SCHEMBL11486815 | 0.89 | NPSR1 (0.59) | NPSR1NFKB1BLMHTR1AHTR2A | |
| SCHEMBL23501871 | 0.89 | GAA (0.58) | NPSR1NFKB1BLMHTR1AHTR2A | |
| SCHEMBL23501868 | 0.89 | GAA (0.58) | NPSR1NFKB1BLMHTR1AHTR2A | |
| SCHEMBL23501915 | 0.88 | KMT2A (0.62) | NPSR1NFKB1BLMHTR1AHTR2A | |
| SCHEMBL23501914 | 0.88 | KMT2A (0.62) | NPSR1NFKB1BLMHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021118318-A2 | NOVEL INDOLE DERIVATIVE AND USE THEREOF | 주식회사 메타센테라퓨틱스 | 2021-06-17 | — | — | WO | disclosed |
| CN-103804270-B | 5-(4-amidino benzyloxy) tryptophan derivative, its method for making and application | 中国药科大学 | 2016-06-22 | — | — | CN | disclosed |
| CN-103755686-B | The piperidyl with platelet aggregation inhibitory activity replaces 5-hydroxyryptophan derivative | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2016-05-11 | — | — | CN | disclosed |
| CN-103804270-A | 5-(4-amidinobenzyloxy) tryptophan derivatives and preparation method and application thereof | UNIV CHINA PHARMA | 2014-05-21 | — | — | CN | disclosed |
| CN-103755686-A | Piperidyl substituted 5-hydroxytryptophane derivatives with anti-platelet aggregation activity | UNIV CHINA PHARMA | 2014-04-30 | — | — | CN | disclosed |