Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 6/20 | 0.53 |
| ▸ | CSNK1E | P49674 | 6/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23508404 | 0.92 | CSNK1D (0.44) | CSNK1DCSNK1EDRD4GRM2HSD17B10 | |
| SCHEMBL30013457 | 0.92 | CSNK1D (0.44) | CSNK1DCSNK1EDRD4GRM2HSD17B10 | |
| SCHEMBL23497861 | 0.92 | CSNK1D (0.44) | CSNK1DCSNK1EDRD4GRM2HSD17B10 | |
| SCHEMBL23497452 | 0.91 | CSNK1D (0.44) | CSNK1DCSNK1EDRD4GRM2HSD17B10 | |
| SCHEMBL30013448 | 0.91 | CSNK1D (0.44) | CSNK1DCSNK1EDRD4GRM2HSD17B10 | |
| SCHEMBL23508263 | 0.90 | CSNK1D (0.53) | CSNK1DCSNK1EHTR3ADRD4GRM2 | |
| SCHEMBL23508258 | 0.90 | CSNK1E (0.53) | CSNK1DCSNK1EGSK3B | |
| SCHEMBL23508544 | 0.88 | CSNK1D (0.42) | CSNK1DCSNK1EDRD4GRM2HSD17B10 | |
| SCHEMBL23508548 | 0.88 | CSNK2A1 (0.46) | CSNK1DCSNK1EDRD4GRM2PKM | |
| SCHEMBL23497601 | 0.88 | CSNK1D (0.41) | CSNK1DCSNK1EDRD4GRM2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117034-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-20 | — | — | US | disclosed |
| WO-2021116178-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117034-A1 | PYRAZOLOTRIAZINES | BRCA1, TPX2, CCND2 | CSNK1D 963/4885CSNK1E 1596/4885HTR3A 2904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.