Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.33 |
| ▸ | CCNK | O75909 | 2/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 5/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.33 |
| ▸ | CDK9 | P50750 | 3/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.33 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23508626 | 0.90 | CDK12 (0.41) | CDK12CCNKCSNK1ECSNK1DCDK9 | |
| SCHEMBL23508494 | 0.90 | CSNK1E (0.40) | CDK12CCNKCSNK1ECSNK1DCDK9 | |
| SCHEMBL23508625 | 0.89 | MEN1 (0.33) | MEN1PSMD14MMP2MAPTKMT2A | |
| SCHEMBL23508333 | 0.87 | CDK12 (0.36) | CDK12CCNKCSNK1ECSNK1DCDK9 | |
| SCHEMBL25140223 | 0.86 | CSNK1D (0.38) | MAPTCSNK1ECSNK1DGSK3B | |
| SCHEMBL23508458 | 0.85 | CSNK1E (0.43) | MEN1PSMD14MMP2MAPTKMT2A | |
| SCHEMBL23508338 | 0.84 | IDO1 (0.31) | CSNK1E | |
| SCHEMBL23508470 | 0.84 | CDK12 (0.47) | CDK12CCNKCSNK1ECSNK1DCDK9 | |
| SCHEMBL23508634 | 0.82 | CSNK1D (0.41) | MAPTKMT2ACSNK1ECSNK1D | |
| SCHEMBL23508389 | 0.82 | PDE10A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117034-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-20 | — | — | US | disclosed |
| WO-2021116178-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117034-A1 | PYRAZOLOTRIAZINES | BRCA1, TPX2, CCND2 | MEN1 172/4885PSMD14 3143/4885MMP2 4446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.