Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 4/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23508341 | 0.90 | CDK2 (0.33) | CDK2KLK1KLK5GSK3B | |
| SCHEMBL23508247 | 0.89 | GSK3B (0.33) | CDK2GSK3B | |
| SCHEMBL23497790 | 0.88 | KLK1 (0.36) | CDK2KLK1KLK5GSK3BCSNK1D | |
| SCHEMBL23508064 | 0.83 | GSK3B (0.36) | PTGS2CDK2KLK1KLK5GSK3B | |
| SCHEMBL23508347 | 0.82 | GSK3B (0.34) | PTGS2CDK2KLK1KLK5GSK3B | |
| SCHEMBL23508421 | 0.80 | CSNK1D (0.48) | CDK2GSK3BHRH4CSNK1DCSNK1E | |
| SCHEMBL23508316 | 0.80 | CACNA1H (0.35) | CDK2GSK3BHRH4 | |
| SCHEMBL23508237 | 0.78 | CSNK1E (0.48) | GSK3BCSNK1DCSNK1E | |
| SCHEMBL25140202 | 0.77 | SMN1; SMN2 (0.31) | KLK1KLK5 | |
| SCHEMBL23508299 | 0.73 | GSK3B (0.36) | CDK2KLK1KLK5GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073072-A1 | PYRAZOLOTRIAZINES | Bayer Aktiengesellschaft (DE) | 2022-10-19 | — | — | EP | disclosed |
| CN-115023427-A | Pyrazolotriazines | 拜耳公司 | 2022-09-06 | — | — | CN | disclosed |
| WO-2021116178-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-17 | — | — | WO | disclosed |