Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 14/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 12/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23508670 | 0.90 | CSNK1E (0.43) | CSNK1ECSNK1D | |
| SCHEMBL23508213 | 0.89 | CSNK1E (0.45) | CSNK1ECSNK1DCDK2HRH4HTR2C | |
| SCHEMBL23508574 | 0.88 | CSNK1E (0.42) | CSNK1ECSNK1DCDK2HRH4USP2 | |
| SCHEMBL23508385 | 0.88 | CSNK1E (0.41) | CSNK1ECSNK1DCDK2KCNH2HRH4 | |
| SCHEMBL25140214 | 0.88 | CSNK1E (0.40) | CSNK1ECSNK1DDGAT1SOAT1KCNH2 | |
| SCHEMBL23508421 | 0.87 | CSNK1D (0.48) | CSNK1ECSNK1DCDK2HRH4HTR3A | |
| SCHEMBL23508550 | 0.86 | CSNK1D (0.49) | CSNK1ECSNK1DCDK2HRH4HTR2C | |
| SCHEMBL25140221 | 0.85 | CSNK1E (0.53) | CSNK1ECSNK1DCDK2 | |
| SCHEMBL23508338 | 0.85 | IDO1 (0.31) | CSNK1E | |
| SCHEMBL23508263 | 0.85 | CSNK1D (0.53) | CSNK1ECSNK1DCDK2HRH4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117034-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-20 | — | — | US | disclosed |
| WO-2021116178-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117034-A1 | PYRAZOLOTRIAZINES | BRCA1, TPX2, CCND2 | CSNK1E 1596/4885CSNK1D 963/4885CDK2 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.