Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 10/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 8/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.34 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.34 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23497407 | 0.92 | CSNK1D (0.44) | CSNK1ECSNK1DMTORPIK3CAATM | |
| SCHEMBL23497525 | 0.89 | CSNK1D (0.40) | CSNK1ECSNK1DMTORPIK3R1PIK3CA | |
| SCHEMBL30590445 | 0.88 | PIK3CA (0.40) | CSNK1ECSNK1DMTORPIK3R1PIK3CA | |
| SCHEMBL23497445 | 0.88 | CSNK1E (0.40) | CSNK1ECSNK1DCYP1A2USP2ALDH1A1 | |
| SCHEMBL30590497 | 0.86 | CSNK1E (0.37) | CSNK1ECSNK1DMTORPIK3R1CYP1A2 | |
| SCHEMBL25307846 | 0.86 | CSNK1E (0.37) | CSNK1ECSNK1DMTORPIK3R1CYP1A2 | |
| SCHEMBL25305733 | 0.85 | SCN9A (0.38) | CSNK1ECSNK1DPRKDCTDP1 | |
| SCHEMBL25300076 | 0.85 | CSNK1E (0.37) | CSNK1ECSNK1DMTORPIK3R1PIK3CB | |
| SCHEMBL25263677 | 0.83 | CSNK1E (0.36) | CSNK1ECSNK1DMTORPIK3R1PIK3CA | |
| SCHEMBL25256993 | 0.83 | PIK3CA (0.37) | CSNK1ECSNK1DMTORPTK2PIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117034-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-20 | — | — | US | claimed |
| EP-4073072-A1 | PYRAZOLOTRIAZINES | Bayer Aktiengesellschaft (DE) | 2022-10-19 | — | — | EP | claimed |
| US-20230117034-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-20 | — | — | US | disclosed |
| US-20230117034-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-20 | — | — | US | disclosed |
| EP-4073072-A1 | PYRAZOLOTRIAZINES | Bayer Aktiengesellschaft (DE) | 2022-10-19 | — | — | EP | disclosed |
| WO-2021116178-A1 | PYRAZOLOTRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117034-A1 | PYRAZOLOTRIAZINES | BRCA1, TPX2, CCND2 | CSNK1E 1596/4885CSNK1D 963/4885MTOR 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.