Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.80 |
| ▸ | CA4 | P22748 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL30090890 | 1.00 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL29285074 | 1.00 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL29649307 | 0.95 | CA1 (0.89) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL19962 | 0.95 | CA1 (0.89) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL25334487 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL25215531 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL21752845 | 0.90 | — | — | |
| Acetic Acid SCHEMBL23116337 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL21752870 | 0.90 | — | — | |
| Acetic Acid SCHEMBL21752943 | 0.90 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9881791-B2 | Method for producing an oxide film using a low temperature process, an oxide film and an electronic device thereof | KOREA ELECTRONICS TECHNOLOGY INSTITUTE (KR) | 2018-01-30 | — | — | US | claimed |
| US-20150123115-A1 | METHOD FOR PRODUCING AN OXIDE FILM USING A LOW TEMPERATURE PROCESS, AN OXIDE FILM AND AN ELECTRONIC DEVICE THEREOF | KOREA ELECTRONICS TECHNOLOGY INSTITUTE (KR) | 2015-05-07 | — | — | US | claimed |
| EP-2840590-A1 | METHOD FOR PRODUCING AN OXIDE FILM USING A LOW TEMPERATURE PROCESS, AN OXIDE FILM AND AN ELECTRONIC DEVICE THEREOF | Korea Electronics Technology Institute (KR) | 2015-02-25 | — | — | EP | claimed |
| CN-109742156-A | The preparation method of thin film transistor (TFT), display device and thin film transistor (TFT) | 云谷（固安）科技有限公司 | 2019-05-10 | — | — | CN | disclosed |
| US-9881791-B2 | Method for producing an oxide film using a low temperature process, an oxide film and an electronic device thereof | KOREA ELECTRONICS TECHNOLOGY INSTITUTE (KR) | 2018-01-30 | — | — | US | disclosed |
| US-20150123115-A1 | METHOD FOR PRODUCING AN OXIDE FILM USING A LOW TEMPERATURE PROCESS, AN OXIDE FILM AND AN ELECTRONIC DEVICE THEREOF | KOREA ELECTRONICS TECHNOLOGY INSTITUTE (KR) | 2015-05-07 | — | — | US | disclosed |
| EP-2840590-A1 | METHOD FOR PRODUCING AN OXIDE FILM USING A LOW TEMPERATURE PROCESS, AN OXIDE FILM AND AN ELECTRONIC DEVICE THEREOF | Korea Electronics Technology Institute (KR) | 2015-02-25 | — | — | EP | disclosed |
| US-8362433-B2 | X-ray detector fabrication methods and apparatus therefrom | GENERAL ELECTRIC COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| US-20110260377-A1 | X-RAY DETECTOR FABRICATION METHODS AND APPARATUS THEREFROM | GE Precision Healthcare LLC | 2011-10-27 | — | — | US | disclosed |
| US-8008624-B2 | X-ray detector fabrication methods and apparatus therefrom | GENERAL ELECTRIC COMPANY (US) | 2011-08-30 | — | — | US | disclosed |
| US-20080170656-A1 | X-Ray Detector Fabrication Methods and Apparatus Therefrom | GE Precision Healthcare LLC | 2008-07-17 | — | — | US | disclosed |
| CN-1922104-A | Metal oxide particle and its use | NIPPON CATALYTIC CHEM IND (JP) | 2007-02-28 | — | — | CN | disclosed |