Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIE | Q9UNP9 | 1/20 | 0.71 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.31 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23512383 | 0.92 | PPIE (0.84) | PPIEANPEPLNPEPSLC40A1 | |
| SCHEMBL25146777 | 0.86 | PPIE (0.87) | PPIESLC40A1 | |
| SCHEMBL23512446 | 0.86 | PPIE (0.86) | PPIESLC40A1 | |
| SCHEMBL23512450 | 0.85 | PPIE (0.90) | PPIESLC40A1 | |
| SCHEMBL23512455 | 0.85 | PPIE (0.86) | PPIESLC40A1 | |
| SCHEMBL25146434 | 0.84 | PPIE (0.94) | PPIEANPEPLNPEPSLC40A1 | |
| SCHEMBL23512908 | 0.84 | PPIE (0.90) | PPIESLC40A1 | |
| SCHEMBL25146703 | 0.83 | PPIE (0.96) | PPIEANPEPLNPEPSLC40A1 | |
| SCHEMBL23512388 | 0.83 | PPIE (1.00) | PPIEANPEPLNPEPSLC40A1 | |
| SCHEMBL23512386 | 0.83 | PPIE (0.91) | PPIEANPEPLNPEPSLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119249-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-06-17 | — | — | WO | disclosed |