SCHEMBL235131

SCHEMBL235131

O=C(O)C(O)Cc1ccc(O)cc1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.63
SLC7A5 Q01650 1/20 0.62
CA2 P00918 1/20 0.50
CAMK2A Q9UQM7 1/20 0.50
MME P08473 1/20 0.49
ACE P12821 1/20 0.49
ESR1 P03372 4/20 0.48
ESR2 Q92731 4/20 0.48
TRPV1 Q8NER1 1/20 0.47
POLB P06746 1/20 0.47
TAAR1 Q96RJ0 3/20 0.47
SLC6A2 P23975 1/20 0.47
FOLH1 Q04609 1/20 0.46
NAALAD2 Q9Y3Q0 1/20 0.46
FNTA P49354 1/20 0.45
FNTB P49356 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8323543 1.00 KDM6B (0.63) KDM6BSLC7A5CA2CAMK2AMME
SCHEMBL1067448 1.00 KDM6B (0.63) KDM6BSLC7A5CA2CAMK2AMME
SCHEMBL289562 1.00 KDM6B (0.63) KDM6BSLC7A5CA2CAMK2AMME
Water SCHEMBL4812235 0.98 KDM6B (0.61) KDM6BSLC7A5CA2CAMK2AMME
SCHEMBL10891346 0.91 KDM6B (0.67) KDM6BSLC7A5MMEACEESR1
Tyrosine SCHEMBL17164596 0.89 SLC7A5 (0.83) KDM6BSLC7A5
Hydroxyphenyl Propionic Acid SCHEMBL20377973 0.89 TRPV1 (0.55) KDM6BSLC7A5CA2CAMK2AESR1
SCHEMBL2705803 0.86 KDM6B (0.53) KDM6BSLC7A5MMEACEESR1
SCHEMBL7559115 0.85 KDM6B (0.53) KDM6BSLC7A5MMEACETRPV1
Phenylalanine SCHEMBL17731626 0.85 SLC7A5 (0.75) KDM6BSLC7A5TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2211 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-20260123658-A1 Methods of Increasing the Beneficial Properties of Fermented Foods The Brd. of Trustees of the Univ. of Illinois (US) 2026-05-07 US claimed
EP-4731643-A2 COMPOSITIONS AND METHODS FOR REDUCING PAIN AND INFLAMMATION THROUGH EPIGENETIC MODULATION Navega Therapeutics, Inc. (US) 2026-04-29 EP claimed
EP-4713452-A2 COMPOSITIONS AND METHODS FOR MULTIPLEX EPIGENETIC REGULATION nChroma Bio, Inc. (US) 2026-03-25 EP claimed
EP-4713451-A2 COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF CD3GAMMA, CD3DELTA, AND RFX5 EXPRESSION nChroma Bio, Inc. (US) 2026-03-25 EP claimed
EP-4677082-A2 COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF PCSK9 EXPRESSION nChroma Bio, Inc. (US) 2026-01-14 EP claimed
US-20250258146-A1 QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP HUMAN METABOLOMICS INSTITUTE INC. (CN) 2025-08-14 US claimed
WO-2025133394-A1 METABOLIC FINGERPRINTING OF SALIVA SAMPLES USING NMR MAVEN HEALTH GMBH (CH) 2025-06-26 WO claimed
CN-120138032-A Application of NtFAAH gene in regulating and controlling organic acid metabolism of tobacco and cultivating cold-sensitive tobacco strain 中国烟草总公司郑州烟草研究院 2025-06-13 CN claimed
US-20250163356-A1 SYSTEMS AND METHODS FOR REJUVENATING CELL CULTURE MEDIUM FUTURE MEAT TECHNOLOGIES LTD. (IL) 2025-05-22 US claimed
US-5554597-A Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging TRISTRATA INC (US) 1996-09-10 US claimed
EP-0273202-B1 Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. SCOTT EUGENE J VAN (US) 1995-06-21 EP claimed
EP-0599819-A2 Additives enhancing topical actions of therapeutic agents Van Scott, Eugene J., Dr. (US) 1994-06-01 EP claimed
EP-0374184-B1 CELL GROWTH INHIBITORS AND METHODS OF TREATING CANCER AND CELL PROLIFERATIVE DISEASES BAYLOR COLLEGE MEDICINE (US) 1994-01-12 EP claimed
WO-1993001824-A1 COMBINATION THERAPY USING BIOFLAVONOID COMPOUNDS WITH ANTI-CANCER DRUGS BAYLOR COLLEGE OF MEDICINE (US) 1993-02-04 WO claimed
WO-1992018116-A1 COMPOSITIONS COMPRISING 2-HYDROXYCARBOXYLIC ACIDS AND RELATED COMPOUNDS, AND METHODS FOR ALLEVIATING SIGNS OF DERMATOLOGICAL AGING YU RUEY J (US) 1992-10-29 WO claimed
EP-0508324-A2 Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging Yu, Ruey J., Dr. (US) 1992-10-14 EP claimed
US-5091171-A Skin disorders IGI, INC. 1992-02-25 US claimed
EP-0273202-A2 Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. Van Scott, Eugene J., Dr. (US) 1988-07-06 EP claimed
US-4363815-A Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions YU RUEY J 1982-12-14 US claimed