⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL236994 | 0.97 | — | — | |
| SCHEMBL95866 | 0.87 | — | — | |
| SCHEMBL30899237 | 0.83 | — | — | |
| SCHEMBL30569675 | 0.83 | — | — | |
| SCHEMBL11048189 | 0.79 | — | — | |
| SCHEMBL2089943 | 0.77 | GGPS1 (0.30) | — | |
| SCHEMBL2097302 | 0.77 | GGPS1 (0.30) | — | |
| SCHEMBL179994 | 0.72 | — | — | |
| SCHEMBL9113187 | 0.71 | — | — | |
| SCHEMBL7096585 | 0.71 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427429-B1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | ABBVIE DEUTSCHLAND (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-9567325-B2 | Carboxamide compounds and their use as calpain inhibitors | AbbVie Deutschland GmbH & Co. KG (DE) | 2017-02-14 | — | — | US | disclosed |
| EP-2648731-B1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS V | ABBVIE DEUTSCHLAND (DE) | 2017-01-25 | — | — | EP | disclosed |
| US-9527811-B2 | Carboxamide compounds and their use as calpain inhibitors | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-12-27 | — | — | US | disclosed |
| CN-105968090-A | Carboxamide compounds and their use as calpain inhibitors | ABBVIE 公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-102959660-B | Comprise hydroxamic acid derivs or its salt photoelectric conversion device and preparation method thereof as additive | 巴斯夫欧洲公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-105732581-A | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS IV | ABBVIE 公司 | 2016-07-06 | — | — | CN | disclosed |
| EP-2237774-B1 | THE USE OF 6-HALOGENO-(1,2,4)-TRIAZOLO-(1,5-a)-PYRIMIDINE COMPOUNDS FOR COMBATING PESTS IN AND ON ANIMALS | MERIAL LTD (US) | 2016-06-22 | — | — | EP | disclosed |
| US-9150553-B2 | Carboxamide compounds and their use as calpain inhibitors | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-10-06 | — | — | US | disclosed |
| US-9150545-B2 | Carboxamide compounds and their use as calpain inhibitors V | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-10-06 | — | — | US | disclosed |
| US-6150303-A | Substituted 3-phenylisoxazolines | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-21 | — | — | US | disclosed |
| WO-2000026194-A1 | NOVEL 1-ARYL-4-THIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-11 | — | — | WO | disclosed |
| WO-2000023413-A1 | METHOD FOR DRYING PHENOXYMETHYLBENZOIC ACIDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-27 | — | — | WO | disclosed |
| WO-1999055156-A2 | THE USE OF DERIVATIVES OF IMINOTRIAZOLE AS CROP PROTECTION AGENTS AND NOVEL IMINOTRIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-04 | — | — | WO | disclosed |
| WO-1999050243-A1 | THE USE OF DERIVATIVES OF 2-OXOPYRROLE AS CROP PROTECTION AGENTS AND NOVEL 2-OXOPYRROLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-07 | — | — | WO | disclosed |
| WO-1999018082-A1 | NOVEL SUBSTITUTED PYRIDAZINONES | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-15 | — | — | WO | disclosed |
| EP-0891336-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-20 | — | — | EP | disclosed |
| EP-0835248-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |
| WO-1997001543-A1 | 1-AMINO-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |