⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23526342 | 1.00 | — | — | |
| SCHEMBL23526346 | 1.00 | — | — | |
| SCHEMBL25839110 | 0.86 | BACE1 (0.35) | — | |
| SCHEMBL30493119 | 0.86 | BACE1 (0.35) | — | |
| SCHEMBL31745657 | 0.86 | BACE1 (0.35) | — | |
| SCHEMBL25368179 | 0.81 | KCNJ6 (0.30) | — | |
| SCHEMBL28880422 | 0.79 | BACE1 (0.31) | — | |
| SCHEMBL28880421 | 0.79 | BACE1 (0.31) | — | |
| SCHEMBL28880423 | 0.79 | BACE1 (0.31) | — | |
| SCHEMBL26099899 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250165-A1 | SALTS OF SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-12-28 | — | — | WO | disclosed |
| US-11702418-B2 | SOS1 inhibitors | Mirati Therapeutics, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20230137886-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. | 2023-05-04 | — | — | US | disclosed |
| US-20210188857-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. | 2021-06-24 | — | — | US | disclosed |