SCHEMBL2353428

SCHEMBL2353428

O=C(O)CCCCCCCCCCC[C@]1(C(=O)O)CC[C@H](C(=O)O)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.40
LMNA P02545 4/20 0.40
NFKB1 P19838 1/20 0.40
PMP22 Q01453 1/20 0.40
ALOX15 P16050 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
GRM2 Q14416 2/20 0.36
GRM3 Q14832 2/20 0.36
GRM4 Q14833 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
GRM8 O00222 1/20 0.36
GRM6 O15303 1/20 0.36
GRM5 P41594 1/20 0.36
MTOR P42345 1/20 0.36
GRM1 Q13255 1/20 0.36
PLCB1 Q9NQ66 1/20 0.36
GPR84 Q9NQS5 5/20 0.35
FFAR1 O14842 2/20 0.35
FFAR4 Q5NUL3 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7069470 0.84 TSHR (0.52) TSHRLMNANFKB1PMP22ALOX15
SCHEMBL250989 0.84 TSHR (0.52) TSHRLMNANFKB1PMP22ALOX15
SCHEMBL273244 0.84 TSHR (0.52) TSHRLMNANFKB1PMP22ALOX15
SCHEMBL18263264 0.84 TSHR (0.52) TSHRLMNANFKB1PMP22ALOX15
SCHEMBL18263255 0.84 TSHR (0.52) TSHRLMNANFKB1PMP22ALOX15
SCHEMBL250466 0.84 TSHR (0.52) TSHRLMNANFKB1PMP22ALOX15
SCHEMBL10646768 0.84 TSHR (0.52) TSHRLMNANFKB1PMP22ALOX15
SCHEMBL7088727 0.84 TSHR (0.52) TSHRLMNANFKB1PMP22ALOX15
SCHEMBL113797 0.84 TSHR (0.52) TSHRLMNANFKB1PMP22ALOX15
SCHEMBL8736020 0.83 S1PR5 (0.36) TSHRLMNAALOX15TDP1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1478694-B1 POLYETHERIMIDE COMPOSITION, METHOD, AND ARTICLE SABIC INNOVATIVE PLASTICS IP (NL) 2011-08-10 EP disclosed
EP-0922733-B1 Filled polyetherimide resin compositions GEN ELECTRIC (US) 2006-05-10 EP disclosed
EP-1478694-A1 POLYETHERIMIDE COMPOSITION, METHOD, AND ARTICLE GENERAL ELECTRIC COMPANY (US) 2004-11-24 EP disclosed
US-6753365-B2 MIXTURE WITH ACID ADJUVANT GENERAL ELECTRIC COMPANY 2004-06-22 US disclosed
US-6646031-B2 Molding materials GENERAL ELECTRIC COMPANY 2003-11-11 US disclosed
US-20030171469-A1 Mixture with acid adjuvant SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2003-09-11 US disclosed
WO-2003070828-A1 POLYETHERIMIDE COMPOSITION, METHOD, AND ARTICLE GENERAL ELECTRIC COMPANY (US) 2003-08-28 WO disclosed
EP-0913408-B1 Process for making poly(alkyl (meth)acrylate) rubber latex GEN ELECTRIC (US) 2003-07-23 EP disclosed
US-20020132932-A1 Polyetherimide resin/polyester resin blends having improved visual clarity SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2002-09-19 US disclosed
US-6403684-B1 RESISTANCE TO ELEVATED TEMPERATURE AND IMPROVED IMPACT PROPERTIES GENERAL ELECTRIC COMPANY 2002-06-11 US disclosed
US-6204340-B1 VISUALLY CLEAR THERMOPLASTIC RESIN INCLUDE A POLYETHERIMIDE RESIN, A FIRST POLYESTER RESIN CONTAINS A CYCLOALKYLENE DIOL MONOMER AND TEREPHTHALIC ACID, SECOND POLYESTER CONTAINS A COPOLYMER OF ABOVE ESTER MONOMERS WITH ACYCLIC DIOL GENERAL ELECTRIC COMPANY 2001-03-20 US disclosed
US-6111031-A A THERMOPLASTIC RESIN COMPRISES OF A POLYETHERIMIDE POLYMER, AN INERT PARTICULATE FILLER AND A GLOSS-ENHANCING ADDITIVE SELECTED FROM LINEAR POLYSILOXANE, POLYETHYLENE AND CRYSTALLINE THERMOPLASTIC RESIN TO IMPROVE THE SURFACE GLOSS GENERAL ELECTRIC COMPANY (US) 2000-08-29 US disclosed
US-6063874-A IN SPECIFIC PARTS BY WEIGHT, ALSO CONTAINING A PHENOL-CONTAINING OR PHOSPHORUS-CONTAINING STABILIZER TO INCREASE COLOR STABILITY GENERAL ELECTRIC CO. (US) 2000-05-16 US disclosed
US-5939497-A CLEAR THERMOPLASTIC RESIN COMPOSITIONS INCLUDE A POLYETHERIMIDE RESIN, A FIRST POLYESTER RESIN AND A SECOND POLYESTER RESIN, EXHIBIT RESISTANCE TO ELEVATED TEMPERATURE AND IMPROVED IMPACT PROPERTIES GENERAL ELECTRIC COMPANY (US) 1999-08-17 US disclosed
EP-0922733-A2 Filled polyetherimide resin compositions GENERAL ELECTRIC COMPANY (US) 1999-06-16 EP disclosed
EP-0913408-A2 A process for making a poly(Alkyl (Meth)Acrylate) rubber latex GENERAL ELECTRIC COMPANY (US) 1999-05-06 EP disclosed
EP-0900828-A1 Polyetherimide resin/polyester resin blends GENERAL ELECTRIC COMPANY (US) 1999-03-10 EP disclosed