SCHEMBL2353469

SCHEMBL2353469

CN1CC=CC=C1/C=N\O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2353471 1.00 POLB (0.31) POLBCYP2C19
SCHEMBL30456698 1.00 POLB (0.31) POLBCYP2C19
Hydrochloric Acid SCHEMBL11816180 0.98 POLB (0.30) POLBCYP2C19
Hydrochloric Acid SCHEMBL11816174 0.98 POLB (0.30) POLBCYP2C19
SCHEMBL8071026 0.74
SCHEMBL311601 0.72
SCHEMBL4343624 0.72
SCHEMBL11665315 0.67
SCHEMBL2541407 0.64
SCHEMBL11103519 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3962447-A Novel pro-drug derivatives of pyridinium aldoxime type cholinesterase reactivators and method of using same INTERX RESEARCH CORPORATION (US) 1976-06-08 US claimed
US-20110230473-A1 Methods and Compositions for Treating Status Epilepticus and Seizures Causing Status Epilepticus GORDON RICHARD K 2011-09-22 US disclosed
EP-2355818-A2 METHODS AND COMPOSITIONS FOR TREATING STATUS EPILEPTICUS AND SEIZURES CAUSING STATUS EPILEPTICUS The United States of America, as represented by The Secretary of The Army, on behalf of Walter Reed Army Institute of Research (US) 2011-08-17 EP disclosed
WO-2010042780-A2 METHODS AND COMPOSITIONS FOR TREATING STATUS EPILEPTICUS AND SEIZURES CAUSING STATUS EPILEPTICUS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY, ON BEHALF OF WALTER REED ARMY INSTITUTE OF RESEARCH (US) 2010-04-15 WO disclosed
US-3962447-A Novel pro-drug derivatives of pyridinium aldoxime type cholinesterase reactivators and method of using same INTERX RESEARCH CORPORATION (US) 1976-06-08 US disclosed