Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123838 | 1.00 | PRMT5 (0.60) | PRMT5WDR77 | |
| SCHEMBL474871 | 0.86 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL12031482 | 0.86 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL733472 | 0.86 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL12447408 | 0.86 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL23896930 | 0.81 | PRMT5 (0.49) | PRMT5WDR77 | |
| SCHEMBL20733586 | 0.81 | PRMT5 (0.61) | PRMT5WDR77 | |
| SCHEMBL20721553 | 0.81 | PRMT5 (0.42) | PRMT5WDR77 | |
| SCHEMBL20733594 | 0.81 | PRMT5 (0.42) | PRMT5WDR77 | |
| SCHEMBL23896929 | 0.80 | PRMT5 (0.61) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021126999-A1 | USE OF BIOMARKERS IN IDENTIFYING PATIENTS THAT WILL BE RESPONSIVE TO TREATMENT WITH A PRMT5 INHIBITOR | MERCK SHARP & DOHME CORP. (US) | 2021-06-24 | — | — | WO | disclosed |