Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.49 |
| ▸ | MCOLN2 | Q8IZK6 | 2/20 | 0.49 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535974 | 0.90 | MCOLN3 (0.50) | ALDH1A1KDM4ELMNAHPGDMCOLN3 | |
| SCHEMBL23057075 | 0.88 | MCOLN3 (0.53) | ALDH1A1KDM4ELMNAHPGDMCOLN3 | |
| SCHEMBL29947245 | 0.86 | MCOLN3 (0.50) | ALDH1A1KDM4ELMNAHPGDMCOLN3 | |
| SCHEMBL23057079 | 0.85 | MCOLN3 (0.53) | ALDH1A1KDM4ELMNAHPGDMCOLN3 | |
| SCHEMBL29931953 | 0.85 | MCOLN3 (0.48) | ALDH1A1KDM4ELMNAHPGDMCOLN3 | |
| SCHEMBL29931845 | 0.85 | MCOLN3 (0.48) | ALDH1A1KDM4ELMNAHPGDMCOLN3 | |
| SCHEMBL29932013 | 0.85 | MCOLN3 (0.48) | ALDH1A1KDM4ELMNAHPGDMCOLN3 | |
| SCHEMBL23554963 | 0.85 | MCOLN3 (0.48) | ALDH1A1KDM4ELMNAHPGDMCOLN3 | |
| SCHEMBL23057263 | 0.85 | MCOLN3 (0.48) | ALDH1A1KDM4ELMNAHPGDMCOLN3 | |
| SCHEMBL23043799 | 0.84 | MCOLN3 (0.55) | ALDH1A1KDM4ELMNAHPGDMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |