Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.30 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10802747 | 1.00 | TDP1 (0.40) | TDP1SMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL29974453 | 0.84 | TDP1 (0.39) | TDP1SMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL28531439 | 0.82 | ECE1 (0.32) | — | |
| SCHEMBL7536347 | 0.80 | TDP1 (0.43) | TDP1SMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL6006627 | 0.80 | TDP1 (0.43) | TDP1SMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL196267 | 0.80 | TDP1 (0.43) | TDP1SMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL19741547 | 0.80 | TDP1 (0.43) | TDP1SMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL196268 | 0.80 | TDP1 (0.43) | TDP1SMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2186107 | 0.78 | TDP1 (0.42) | TDP1SMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8968540 | 0.78 | TDP1 (0.42) | TDP1SMN1; SMN2ALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687557-A | MIXTURE OF CYANIDE COMPLEXES OF GOLD, COPPER, CADMIUM, AND ZINC | EMMENEGGER HEINZ (CH) | 1987-08-18 | — | — | US | claimed |
| EP-2356141-A1 | PROCESS FOR THE PURIFICATION OF HUMAN GROWTH HORMONE POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS | Novo Nordisk A/S (DK) | 2011-08-17 | — | — | EP | disclosed |