Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.54 |
| ▸ | PPARA | Q07869 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353699 | 1.00 | PPARG (0.54) | PPARGPPARANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL475127 | 0.91 | PPARG (0.56) | PPARGPPARANPC1ALDH1A1MEN1 | |
| SCHEMBL2978389 | 0.91 | PPARG (0.56) | PPARGPPARANPC1ALDH1A1MEN1 | |
| SCHEMBL475130 | 0.91 | PPARG (0.56) | PPARGPPARANPC1ALDH1A1MEN1 | |
| SCHEMBL13994554 | 0.86 | PPARG (0.50) | PPARGPPARANPC1ALDH1A1MEN1 | |
| SCHEMBL2719917 | 0.85 | PPARG (0.52) | PPARGPPARANPC1ALDH1A1RAB9A | |
| SCHEMBL2978823 | 0.85 | PPARG (0.52) | PPARGPPARANPC1ALDH1A1RAB9A | |
| SCHEMBL2719920 | 0.85 | PPARG (0.52) | PPARGPPARANPC1ALDH1A1RAB9A | |
| SCHEMBL2980280 | 0.85 | PPARG (0.52) | PPARGPPARANPC1ALDH1A1MEN1 | |
| SCHEMBL2980279 | 0.85 | PPARG (0.52) | PPARGPPARANPC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351563-A1 | AGENT FOR TREATMENT OF DIABETES | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2011-08-03 | — | — | EP | disclosed |