Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.70 |
| ▸ | ERBB2 | P04626 | 11/20 | 0.57 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.57 |
| ▸ | JAK3 | P52333 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23537790 | 1.00 | EGFR (0.70) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL23570910 | 0.96 | EGFR (0.72) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL23537739 | 0.90 | EGFR (0.57) | EGFRERBB2ERBB4 | |
| SCHEMBL23537738 | 0.90 | EGFR (0.57) | EGFRERBB2ERBB4 | |
| SCHEMBL23538180 | 0.89 | EGFR (0.56) | EGFRERBB2 | |
| SCHEMBL23538181 | 0.89 | EGFR (0.56) | EGFRERBB2 | |
| SCHEMBL23538057 | 0.88 | EGFR (0.78) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL23538059 | 0.88 | EGFR (0.78) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL23537942 | 0.86 | EGFR (0.67) | EGFRERBB2 | |
| SCHEMBL23537954 | 0.86 | EGFR (0.72) | EGFRERBB2ERBB4JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127397-A1 | NITROGEN HETEROCYCLIC COMPOUNDS AND METHODS OF USE | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021127397-A1 | NITROGEN HETEROCYCLIC COMPOUNDS AND METHODS OF USE | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |