SCHEMBL23542834

SCHEMBL23542834

C#Cc1cc(-c2ccncc2)c(-c2ccc(F)cc2)s1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 19/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17542518 0.83 MAPK14 (1.00) MAPK14
SCHEMBL17542578 0.80 MAPK14 (0.82) MAPK14
SCHEMBL19367817 0.80 MAPK14 (0.79) MAPK14
SCHEMBL17542505 0.79 MAPK14 (1.00) MAPK14
SCHEMBL19367800 0.78 MAPK14 (0.80) MAPK14
SCHEMBL17542510 0.78 MAPK14 (1.00) MAPK14
SCHEMBL23542847 0.77 MAPK14 (0.68) MAPK14
SCHEMBL17542566 0.77 MAPK14 (1.00) MAPK14
SCHEMBL17552066 0.77 MAPK14 (1.00) MAPK14
SCHEMBL23542852 0.75 MAPK14 (0.75) MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3186245-B1 MAPK INHIBITORS EverBrilliant Pharma Pty Ltd (AU) 2021-06-23 — — EP disclosed
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