SCHEMBL23544360

SCHEMBL23544360

Cc1ccc(CC(N=C(c2ccccc2)c2ccccc2)C(=O)OC(C)(C)C)c(C)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 1/20 0.58
PSMB5 P28074 4/20 0.39
PSMB8 P28062 1/20 0.39
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
GRIN2B Q13224 1/20 0.36
MAPT P10636 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLC7A5 Q01650 1/20 0.35
ITGA4 P13612 2/20 0.34
ITGB7 P26010 2/20 0.34
CYP2C9 P11712 1/20 0.34
POLB P06746 1/20 0.34
HTT P42858 1/20 0.34
MRGPRX4 Q96LA9 1/20 0.33
KDM4A O75164 1/20 0.33
KDM5A P29375 1/20 0.33
KDM2B Q8NHM5 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
KDM5B Q9UGL1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25946371 0.89 AAK1 (0.56) AAK1RAB9AMAPTSMN1; SMN2SLC7A5
SCHEMBL17586851 0.89 AAK1 (0.58) AAK1NPC1RAB9AMAPTSLC7A5
SCHEMBL21029168 0.86 AAK1 (0.60) AAK1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL30949483 0.83 AAK1 (0.62) AAK1NPC1RAB9AMAPTSLC7A5
SCHEMBL21029732 0.83 AAK1 (0.60) AAK1SMN1; SMN2SLC7A5ITGA4ITGB7
SCHEMBL25318130 0.83 AAK1 (0.60) AAK1SLC7A5ITGA4ITGB7
SCHEMBL18482286 0.83 AAK1 (0.54) AAK1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL20235984 0.81 AAK1 (0.57) AAK1NPC1MAPTSLC7A5ITGA4
SCHEMBL20235981 0.81 AAK1 (0.57) AAK1NPC1MAPTSLC7A5ITGA4
SCHEMBL21732895 0.81 AAK1 (0.57) AAK1MAPTSLC7A5ITGA4ITGB7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3838890-A1 METHOD FOR PREPARING 18F-BPA AND INTERMEDIATE Neuboron Medtech Ltd. (CN) 2021-06-23 EP disclosed