Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 6/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23547696 | 1.00 | TSHR (0.39) | TSHRSLC5A2SSTR5CYP3A4CYP2D6 | |
| SCHEMBL26554486 | 0.82 | OGA (0.38) | TSHRSLC5A2EPHX1OGA | |
| SCHEMBL25604827 | 0.81 | TSHR (0.42) | TSHRSSTR5EPHX1SSTR1SSTR2 | |
| SCHEMBL25608169 | 0.80 | SLC5A2 (0.53) | SLC5A2 | |
| SCHEMBL4622393 | 0.79 | TSHR (0.43) | TSHRCYP3A4CYP2D6EPHX1 | |
| SCHEMBL4622391 | 0.79 | TSHR (0.43) | TSHRCYP3A4CYP2D6EPHX1 | |
| SCHEMBL4622395 | 0.79 | TSHR (0.43) | TSHRCYP3A4CYP2D6EPHX1 | |
| SCHEMBL25608052 | 0.77 | SSTR5 (0.39) | SSTR5EPHX1SSTR1SSTR2SSTR4 | |
| SCHEMBL24487718 | 0.77 | TSHR (0.39) | TSHREPHX1 | |
| SCHEMBL25616085 | 0.74 | SSTR5 (0.35) | SLC5A2SSTR5SSTR1SSTR2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210189392-A1 | S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS | ALIGOS THERAPEUTICS, INC. | 2021-06-24 | — | — | US | disclosed |