Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MDK | P21741 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 8/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23555894 | 0.91 | MAPK1 (0.39) | MAPK1LGALS3ESR1PGRHTR1A | |
| SCHEMBL21148565 | 0.90 | MAPK1 (0.45) | MAPK1LGALS3ESR1PGRHTR1A | |
| SCHEMBL20857186 | 0.89 | MAPK1 (0.40) | MAPK1LGALS3ESR1PGRHTR1A | |
| SCHEMBL24797255 | 0.86 | GLP1R (0.41) | GLP1R | |
| SCHEMBL21149201 | 0.86 | MAPK1 (0.40) | MAPK1LGALS3ESR1PGRHTR1A | |
| SCHEMBL19325102 | 0.86 | MAPK1 (0.42) | MAPK1LGALS3ESR1PGRHTR1A | |
| SCHEMBL21148755 | 0.84 | MAPK1 (0.41) | MAPK1LGALS3ESR1PGRHTR1A | |
| SCHEMBL21148564 | 0.84 | MAPK1 (0.36) | MAPK1LGALS3ESR1PGRHTR1A | |
| SCHEMBL23555960 | 0.84 | MAPK1 (0.41) | MAPK1LGALS3ESR1PGRHTR1A | |
| SCHEMBL20857185 | 0.84 | MAPK1 (0.36) | MAPK1LGALS3ESR1PGRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210189394-A1 | Targeting Ligands For Therapeutic Compounds | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210189394-A1 | Targeting Ligands For Therapeutic Compounds | FABP1, SNRPE, HAVCR2 | MAPK1 4176/4885LGALS3 1353/4885ESR1 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.