Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.67 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.49 |
| ▸ | CHUK | O15111 | 2/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.49 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23523816 | 0.88 | GRM5 (0.67) | GRM5CASP3SENP8SENP7SENP6 | |
| SCHEMBL20587476 | 0.88 | GRM5 (0.70) | GRM5HCAR3MAPTTP53NPC1 | |
| SCHEMBL30355823 | 0.88 | GRM5 (0.70) | GRM5HCAR3MAPTTP53NPC1 | |
| SCHEMBL30355736 | 0.87 | GRM5 (0.69) | GRM5HCAR3MAPTTP53MEN1 | |
| SCHEMBL23524285 | 0.87 | GRM5 (0.69) | GRM5HCAR3MAPTTP53MEN1 | |
| SCHEMBL23524288 | 0.85 | GRM5 (0.67) | GRM5HCAR3MAPTTP53KDM4E | |
| SCHEMBL30355533 | 0.85 | GRM5 (0.67) | GRM5HCAR3MAPTTP53KDM4E | |
| SCHEMBL23523793 | 0.85 | GRM5 (0.64) | GRM5CASP3SENP8SENP7SENP6 | |
| SCHEMBL30355635 | 0.85 | GRM5 (0.64) | GRM5CASP3SENP8SENP7SENP6 | |
| SCHEMBL23524398 | 0.84 | GRM5 (0.74) | GRM5HCAR3MAPTTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188826-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | TREVENA, INC. | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188826-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | S1PR1, S1PR2, S1PR3 | GRM5 456/4885CASP3 3079/4885SENP8 3546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.