Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.57 |
| ▸ | FYN | P06241 | 6/20 | 0.57 |
| ▸ | PIM1 | P11309 | 12/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12350665 | 0.88 | MKNK1 (0.57) | MKNK1FYNPIM1KCNH2 | |
| SCHEMBL12699592 | 0.86 | FYN (0.76) | MKNK1FYNPIM1KCNH2 | |
| SCHEMBL3037848 | 0.86 | MKNK1 (0.77) | MKNK1FYNPIM1KCNH2 | |
| SCHEMBL12350660 | 0.86 | FYN (0.61) | MKNK1FYNPIM1KCNH2 | |
| SCHEMBL12351155 | 0.85 | FYN (0.76) | FYNPIM1KCNH2 | |
| SCHEMBL12350824 | 0.85 | MKNK1 (0.54) | MKNK1FYNPIM1KCNH2 | |
| SCHEMBL12699558 | 0.83 | FYN (0.57) | MKNK1FYNPIM1KCNH2 | |
| SCHEMBL12351138 | 0.82 | MKNK1 (0.59) | MKNK1FYNPIM1KCNH2 | |
| SCHEMBL12614356 | 0.80 | MKNK1 (0.55) | MKNK1FYNPIM1KCNH2 | |
| SCHEMBL12351135 | 0.80 | MKNK1 (0.48) | MKNK1FYNPIM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101640-A1 | FUSED HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF MALARIA | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011101640-A1 | FUSED HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF MALARIA | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2011-08-25 | — | — | WO | disclosed |