⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24186984 | 0.79 | — | — | |
| SCHEMBL24782380 | 0.68 | — | — | |
| SCHEMBL24478912 | 0.65 | — | — | |
| SCHEMBL22295936 | 0.61 | — | — | |
| SCHEMBL20937511 | 0.58 | — | — | |
| SCHEMBL18571015 | 0.56 | — | — | |
| SCHEMBL20074493 | 0.56 | — | — | |
| SCHEMBL23892548 | 0.55 | — | — | |
| SCHEMBL20762170 | 0.54 | GSK3A (0.40) | — | |
| SCHEMBL23652402 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2023192686-A1 | METHODS FOR PREVENTING OR SLOWING THE PROGRESSION OF COGNITIVE DECLINE OR IMPAIRMENT IN SUBJECTS DISPLAYING NORMAL COGNITIVE PERFORMANCE | Li shi jiang (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2022011318-A1 | COMBINATIONS OF GABAA ALPHA 5 AGONISTS AND SV2A INHIBITORS AND METHODS OF USING IN THE TREATMENT OF COGNITIVE IMPAIRMENT | AGENEBIO, INC. (US) | 2022-01-13 | — | — | WO | disclosed |
| WO-2021127543-A1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS, AND METHODS FOR TREATING COGNITIVE IMPAIRMENT | AGENEBIO, INC. (US) | 2021-06-24 | — | — | WO | disclosed |