⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22837613 | 0.87 | — | — | |
| SCHEMBL22909134 | 0.87 | — | — | |
| SCHEMBL22856133 | 0.86 | CARM1 (0.34) | — | |
| SCHEMBL23568249 | 0.86 | CARM1 (0.34) | — | |
| SCHEMBL25467745 | 0.86 | — | — | |
| SCHEMBL24508257 | 0.84 | CARM1 (0.34) | — | |
| SCHEMBL25886575 | 0.83 | HTT (0.30) | — | |
| SCHEMBL26280417 | 0.83 | — | — | |
| SCHEMBL25832043 | 0.77 | — | — | |
| SCHEMBL24029376 | 0.77 | CARM1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125800-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |
| US-20210228562-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2021-07-29 | — | — | US | disclosed |
| WO-2021127278-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |