Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 20/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 20/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 3/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24508275 | 0.89 | CARM1 (0.42) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL24607608 | 0.88 | CARM1 (0.41) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL18551309 | 0.86 | CARM1 (0.50) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL20231741 | 0.83 | CARM1 (0.47) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL27307953 | 0.81 | CARM1 (0.43) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL24764433 | 0.81 | NPC1 (0.37) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL25602683 | 0.81 | CARM1 (0.47) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL17285631 | 0.80 | HRH3 (0.41) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL21900666 | 0.80 | — | — | |
| SCHEMBL18551238 | 0.78 | CARM1 (0.51) | CARM1PRMT6PRMT8TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4395549-A1 | COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL | Oerth Bio LLC (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034411-A1 | COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL | OERTH BIO LLC (US) | 2023-03-09 | — | — | WO | disclosed |
| WO-2021127278-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |